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CSS Institute of Molecular Medicine at Windber

CSS Institute of Molecular Medicine at Windber (www.wriwindber.org) is a highly collaborative translational research institute with a mission to improve patient care by advancing cancer research. The Institute has developed a first-class biobanking system to store biospecimens from research participants with or without cancer, accompanied by rich clinicopathologic data which includes treatment and outcome. Data is managed by an advanced informatics infrastructure system developed in-house. We perform both wet-lab and in-silico research on human cancers, using cutting-edge proteogenomic technologies to study DNA, RNA, proteins, and metabolites, etc. Our institute is part of a large research network focused on major pan-cancer projects, with ample funding, rich technological resources, as well as clinical and research domain experts with complementary knowledge that provides a highly collaborative translational research environment.

FULL-TIME POSITIONS

ASSISTANT SCIENTIFIC DIRECTOR
We are in search of a scientist with a proven track record in the life sciences, who is interested in pursuing a management career in a research setting, to fill the position of Assistant Scientific Director reporting to the Chief Scientific Officer (CSO).

Responsibilities:
 Assist the CSO to manage the daily scientific research and business operations of the Institute
 Participate in strategic planning at the Institute level
 Assist the CSO to develop new research programs and collaborations
 Frequently interact with the directors and staff of the institute, as well as external collaborators, to identify issues for improvement and contribute to solution development
 For the successful candidate who desires to continue with scientific career, there is the opportunity to establish a wet-bench or in-silico research lab

Requirements:
 A PhD in life sciences with 5 years of work experience including research and management
 A management degree is a plus but not required
 Demonstrated capabilities to work both independently and as a team player
 Outstanding communication and management skills
 Exhibit a high level of integrity, be respectful, energetic, eager, quick to learn, and dedicated to the position

BIOINFORMATICS SCIENTIST
The Chan Soon-Shiong Institute of Molecular Medicine at Windber (wriwindber.org) has been part of several major national cancer programs, including TCGA and the Cancer Moonshot Initiative. The institute is expanding and is hiring for multiple new Bioinformatics Scientist positions – at the Murtha Cancer Center Research Program (MCCRP) office in Bethesda, MD to join an experienced and highly collaborative team of clinicians, scientists, statisticians, and bioinformaticians in the fight against cancer! The level of the position will be considered based on candidate’s experience.

Key Responsibility:
 Assess diverse clinical, genomic, and proteomic datasets from public domain and internal sources, for discovery as well as designing new projects
 Support projects in the areas of study design, data QC, bioinformatics and statistical analysis, and data management
 Perform analysis of proteogenomic data along with clinic-pathologic data in large cohorts, and synthesize and interpret results for presentations and publications
 Develop or adopt innovative methods and metrics for data QC and predictive model
 Promote the scientific interests of the institute through publication and community interaction

Requirement:
 PhD degree in Bioinformatics or another relevant field, or a MS degree with minimum 3 years of direct experience in bioinformatics, statistics, or computational biology
 Familiar with NGS applications for variant detection/interpretation and gene expression
 Sound scientific logics for tertiary analysis and interpretation, backed by publications
 Strong understanding of concepts and analytical techniques in statistics.
 Proficient in R or another common statistical package.
 Intermediate with Python or another scripting language
 Familiar with Linux environment
 Excellent in written and verbal communication in a collaborative environment
 Self-motivated and good time management with evolving priorities

Desired:
 Experience in translational research or clinical trials, involving genomics or proteomics
 Solid knowledge of cancer biology and cellular pathways
 Familiar with public resources for cancer research and medical genetics
 Experience with computation and data management in a cloud environment
 Familiar with relational database or/and object-oriented database

SENIOR SOFTWARE DEVELOPER
Biomedical Informatics Infrastructure at CSSIMMW is responsible for providing informatics and analytical support to the daily operations of the institute, including support for biomedical informatics research in both technological and scientific fields. This is a senior developer position that is responsible for infrastructure development and supporting the operations of the institute and partners. A strong understanding of databases and software application development is critical to develop and maintain applications and databases, and to conduct data modeling, querying, and analysis. This position requires extensive communications with supervisors, peers, customers, and subordinates.

Bachelors in Computer Science, Information Systems Management, or related technical degree required. Masters is preferred. Six years minimum of application development in C#, C++, Java, or other Object-Oriented language is required. Four years minimum developing web-based applications in a professional environment. Full understanding of Agile development model. Ability to mentor other developers. Extensive full life cycle experience in software development process including requirements analyses, design, architecture, coding, testing and maintenance. Knowledge of script programming language such as Python is a plus. Advanced working experience with relational databases such as Oracle or SQL Server. Ability to use Windows OS and Microsoft Office applications. Abstract preparation and writing is a plus.
Posting Date: February 7, 2025

PROGRAM MANAGER
We are now accepting applications for a full-time Program Manager who will be responsible for using existing workflows and development of new workflows to manage research programs and projects. A main responsibility of the position is budget preparation and execution management. Other duties will include assuring full compliance of all contract requirements, schedules, and provisions; managing project meetings, preparation of reports; and proactively identifying ways to improve program management. This position will be a direct report to the CSO. Bachelor degree of Business Administration or related area is required. MBA will be a plus. 2 years related experience required preferably in a life sciences setting.
Posting Date: February 18, 2025

EQUAL OPPORTUNITY / AFFIRMATIVE ACTION EMPLOYER